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TonB-dependent receptor epitopes expressed in M. bovis BCG induced significant protection in the hamster model of leptospirosis

ABSTRACT: Leptospirosis is an emerging infectious disease caused by pathogenic Leptospira spp. A universal vaccine against leptospirosis is likely to require highly conserved epitopes from pathogenic leptospires that are exposed on the bacterial surface and that generate a protective and sterilizing...

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Detalles Bibliográficos
Autores principales: Bettin, Everton B., Dorneles, Jessica, Hecktheuer, Amanda S., Madruga, Andriele B., Seixas Neto, Amilton C. P., McBride, Alan J. A., Oliveira, Thais L., Grassmann, André A., Dellagostin, Odir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664668/
https://www.ncbi.nlm.nih.gov/pubmed/34893930
http://dx.doi.org/10.1007/s00253-021-11726-9