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Clinical Pharmacokinetics and Pharmacodynamics of Desmoteplase

Desmoteplase is a bat (Desmodus rotundus) saliva-derived fibrinolytic enzyme resembling a urokinase and tissue plasminogen activator. It is highly dependent on fibrin and has some neuroprotective attributes. Intravenous administration of desmoteplase is safe and well tolerated in healthy subjects. P...

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Detalles Bibliográficos
Autores principales: Piechowski-Jozwiak, Bartlomiej, Abidi, Emna, El Nekidy, Wasim S., Bogousslavsky, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664670/
https://www.ncbi.nlm.nih.gov/pubmed/34893967
http://dx.doi.org/10.1007/s13318-021-00743-8