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Drug connectivity mapping and functional analysis reveal therapeutic small molecules that differentially modulate myelination
Disruption or loss of oligodendrocytes (OLs) and myelin has devastating effects on CNS function and integrity, which occur in diverse neurological disorders, including Multiple Sclerosis (MS), Alzheimer’s disease and neuropsychiatric disorders. Hence, there is a need to develop new therapies that pr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editions Scientifiques Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664715/ https://www.ncbi.nlm.nih.gov/pubmed/34813998 http://dx.doi.org/10.1016/j.biopha.2021.112436 |