Drug connectivity mapping and functional analysis reveal therapeutic small molecules that differentially modulate myelination

Disruption or loss of oligodendrocytes (OLs) and myelin has devastating effects on CNS function and integrity, which occur in diverse neurological disorders, including Multiple Sclerosis (MS), Alzheimer’s disease and neuropsychiatric disorders. Hence, there is a need to develop new therapies that pr...

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Detalles Bibliográficos
Autores principales: Rivera, A.D., Pieropan, F., Williams, G., Calzolari, F., Butt, A.M., Azim, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664715/
https://www.ncbi.nlm.nih.gov/pubmed/34813998
http://dx.doi.org/10.1016/j.biopha.2021.112436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664715/
https://www.ncbi.nlm.nih.gov/pubmed/34813998
http://dx.doi.org/10.1016/j.biopha.2021.112436

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