Ileal microbial shifts after Roux-en-Y gastric bypass orchestrate changes in glucose metabolism through modulation of bile acids and L-cell adaptation

Roux-en-Y gastric bypass (RYGB)-induced glycemic improvement is associated with increases in glucagon-like-peptide-1 (GLP-1) secreted from ileal L-cells. We analyzed changes in ileal bile acids and ileal microbial composition in diet-induced-obesity rats after RYGB or sham surgery to elucidate the e...

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Detalles Bibliográficos
Autores principales: Dang, Jerry T., Mocanu, Valentin, Park, Heekuk, Laffin, Michael, Tran, Caroline, Hotte, Naomi, Karmali, Shahzeer, Birch, Daniel W., Madsen, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664817/
https://www.ncbi.nlm.nih.gov/pubmed/34893681
http://dx.doi.org/10.1038/s41598-021-03396-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664817/
https://www.ncbi.nlm.nih.gov/pubmed/34893681
http://dx.doi.org/10.1038/s41598-021-03396-4

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