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Ileal microbial shifts after Roux-en-Y gastric bypass orchestrate changes in glucose metabolism through modulation of bile acids and L-cell adaptation
Roux-en-Y gastric bypass (RYGB)-induced glycemic improvement is associated with increases in glucagon-like-peptide-1 (GLP-1) secreted from ileal L-cells. We analyzed changes in ileal bile acids and ileal microbial composition in diet-induced-obesity rats after RYGB or sham surgery to elucidate the e...
Autores principales: | Dang, Jerry T., Mocanu, Valentin, Park, Heekuk, Laffin, Michael, Tran, Caroline, Hotte, Naomi, Karmali, Shahzeer, Birch, Daniel W., Madsen, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664817/ https://www.ncbi.nlm.nih.gov/pubmed/34893681 http://dx.doi.org/10.1038/s41598-021-03396-4 |
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