Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation

How tubular organs elongate is poorly understood. We found that attenuated ciliary Hedgehog signaling in the gut wall impaired patterning of the circumferential smooth muscle and inhibited proliferation and elongation of developing intestine and esophagus. Similarly, ablation of gut-wall smooth musc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Ying, Paivinen, Pekka, Xie, Chang, Krup, Alexis Leigh, Makela, Tomi P., Mostov, Keith E., Reiter, Jeremy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664829/
https://www.ncbi.nlm.nih.gov/pubmed/34893605
http://dx.doi.org/10.1038/s41467-021-27319-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664829/
https://www.ncbi.nlm.nih.gov/pubmed/34893605
http://dx.doi.org/10.1038/s41467-021-27319-z

Ejemplares similares