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Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation
How tubular organs elongate is poorly understood. We found that attenuated ciliary Hedgehog signaling in the gut wall impaired patterning of the circumferential smooth muscle and inhibited proliferation and elongation of developing intestine and esophagus. Similarly, ablation of gut-wall smooth musc...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664829/ https://www.ncbi.nlm.nih.gov/pubmed/34893605 http://dx.doi.org/10.1038/s41467-021-27319-z |