The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting

Programmed ribosomal frameshifting (PRF) is a fundamental gene expression event in many viruses, including SARS-CoV-2. It allows production of essential viral, structural and replicative enzymes that are encoded in an alternative reading frame. Despite the importance of PRF for the viral life cycle,...

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Detalles Bibliográficos
Autores principales: Zimmer, Matthias M., Kibe, Anuja, Rand, Ulfert, Pekarek, Lukas, Ye, Liqing, Buck, Stefan, Smyth, Redmond P., Cicin-Sain, Luka, Caliskan, Neva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664833/
https://www.ncbi.nlm.nih.gov/pubmed/34893599
http://dx.doi.org/10.1038/s41467-021-27431-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664833/
https://www.ncbi.nlm.nih.gov/pubmed/34893599
http://dx.doi.org/10.1038/s41467-021-27431-0

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