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Dynamic regulation of N(6),2′-O-dimethyladenosine (m(6)Am) in obesity

The prevalent m(6)Am mRNA cap modification was recently identified as a valid target for removal by the human obesity gene FTO along with the previously established m(6)A mRNA modification. However, the deposition and dynamics of m(6)Am in regulating obesity are unknown. Here, we investigate the liv...

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Detalles Bibliográficos
Autores principales: Ben-Haim, Moshe Shay, Pinto, Yishay, Moshitch-Moshkovitz, Sharon, Hershkovitz, Vera, Kol, Nitzan, Diamant-Levi, Tammy, Beeri, Michal Schnaider, Amariglio, Ninette, Cohen, Haim Y., Rechavi, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664860/
https://www.ncbi.nlm.nih.gov/pubmed/34893620
http://dx.doi.org/10.1038/s41467-021-27421-2