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Acute RyR1 Ca(2+) leak enhances NADH-linked mitochondrial respiratory capacity

Sustained ryanodine receptor (RyR) Ca(2+) leak is associated with pathological conditions such as heart failure or skeletal muscle weakness. We report that a single session of sprint interval training (SIT), but not of moderate intensity continuous training (MICT), triggers RyR1 protein oxidation an...

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Detalles Bibliográficos
Autores principales: Zanou, Nadège, Dridi, Haikel, Reiken, Steven, Imamura de Lima, Tanes, Donnelly, Chris, De Marchi, Umberto, Ferrini, Manuele, Vidal, Jeremy, Sittenfeld, Leah, Feige, Jerome N., Garcia-Roves, Pablo M., Lopez-Mejia, Isabel C., Marks, Andrew R., Auwerx, Johan, Kayser, Bengt, Place, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664928/
https://www.ncbi.nlm.nih.gov/pubmed/34893614
http://dx.doi.org/10.1038/s41467-021-27422-1