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Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis

During lung fibrosis, the epithelium induces signaling to underlying mesenchyme to generate excess myofibroblasts and extracellular matrix; herein, we focus on signaling in the mesenchyme. Our studies indicate that platelet-derived growth factor receptor (PDGFR)-β(+) cells are the predominant source...

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Detalles Bibliográficos
Autores principales: Chandran, Rachana R., Xie, Yi, Gallardo-Vara, Eunate, Adams, Taylor, Garcia-Milian, Rolando, Kabir, Inamul, Sheikh, Abdul Q., Kaminski, Naftali, Martin, Kathleen A., Herzog, Erica L., Greif, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664937/
https://www.ncbi.nlm.nih.gov/pubmed/34893592
http://dx.doi.org/10.1038/s41467-021-27499-8