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Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis
During lung fibrosis, the epithelium induces signaling to underlying mesenchyme to generate excess myofibroblasts and extracellular matrix; herein, we focus on signaling in the mesenchyme. Our studies indicate that platelet-derived growth factor receptor (PDGFR)-β(+) cells are the predominant source...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664937/ https://www.ncbi.nlm.nih.gov/pubmed/34893592 http://dx.doi.org/10.1038/s41467-021-27499-8 |