KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion

Metastasis is the main cause of carcinoma-related death, yet we know little about how it initiates due to our inability to visualize stochastic invasion events. Classical models suggest that cells accumulate mutations that first drive formation of a primary mass, and then downregulate epithelia-spec...

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Detalles Bibliográficos
Autores principales: Fadul, John, Zulueta-Coarasa, Teresa, Slattum, Gloria M., Redd, Nadja M., Jin, Mauricio Franco, Redd, Michael J., Daetwyler, Stephan, Hedeen, Danielle, Huisken, Jan, Rosenblatt, Jody
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664939/
https://www.ncbi.nlm.nih.gov/pubmed/34893591
http://dx.doi.org/10.1038/s41467-021-27513-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664939/
https://www.ncbi.nlm.nih.gov/pubmed/34893591
http://dx.doi.org/10.1038/s41467-021-27513-z

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