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KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion
Metastasis is the main cause of carcinoma-related death, yet we know little about how it initiates due to our inability to visualize stochastic invasion events. Classical models suggest that cells accumulate mutations that first drive formation of a primary mass, and then downregulate epithelia-spec...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664939/ https://www.ncbi.nlm.nih.gov/pubmed/34893591 http://dx.doi.org/10.1038/s41467-021-27513-z |