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Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac1 and RhoA

Osteosarcoma (OS) is the most common primary bone tumor. Its high mortality rate and metastasis rate seriously threaten human health. Currently, the treatment has reached a plateau, hence we urgently need to explore new therapeutic directions. In this paper, we found that Trio was highly expressed i...

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Detalles Bibliográficos
Autores principales: Wang, Junyi, Yuan, Lichan, Xu, Xiaohong, Zhang, Zhongyin, Ma, Yuhuan, Hong, Leilei, Ma, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664940/
https://www.ncbi.nlm.nih.gov/pubmed/34893584
http://dx.doi.org/10.1038/s41419-021-04448-3