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Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac1 and RhoA
Osteosarcoma (OS) is the most common primary bone tumor. Its high mortality rate and metastasis rate seriously threaten human health. Currently, the treatment has reached a plateau, hence we urgently need to explore new therapeutic directions. In this paper, we found that Trio was highly expressed i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664940/ https://www.ncbi.nlm.nih.gov/pubmed/34893584 http://dx.doi.org/10.1038/s41419-021-04448-3 |