Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta

Type I collagen (Col1) is the most abundant protein in mammals. Col1 contributes to 90% of the total organic component of bone matrix. However, the precise cellular origin and functional contribution of Col1 in embryogenesis and bone formation remain unknown. Single-cell RNA-sequencing analysis iden...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Yang, Sujuan, Lovisa, Sara, Ambrose, Catherine G., McAndrews, Kathleen M., Sugimoto, Hikaru, Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664945/
https://www.ncbi.nlm.nih.gov/pubmed/34893625
http://dx.doi.org/10.1038/s41467-021-27563-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664945/
https://www.ncbi.nlm.nih.gov/pubmed/34893625
http://dx.doi.org/10.1038/s41467-021-27563-3

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