Potent but transient immunosuppression of T-cells is a general feature of CD71(+) erythroid cells

CD71(+) erythroid cells (CECs) have been recently recognized in both neonates and cancer patients as potent immunoregulatory cells. Here, we show that in mice early-stage CECs expand in anemia, have high levels of arginase 2 (ARG2) and reactive oxygen species (ROS). In the spleens of anemic mice, CE...

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Detalles Bibliográficos
Autores principales: Grzywa, Tomasz M., Sosnowska, Anna, Rydzynska, Zuzanna, Lazniewski, Michal, Plewczynski, Dariusz, Klicka, Klaudia, Malecka-Gieldowska, Milena, Rodziewicz-Lurzynska, Anna, Ciepiela, Olga, Justyniarska, Magdalena, Pomper, Paulina, Grzybowski, Marcin M., Blaszczyk, Roman, Wegrzynowicz, Michal, Tomaszewska, Agnieszka, Basak, Grzegorz, Golab, Jakub, Nowis, Dominika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664950/
https://www.ncbi.nlm.nih.gov/pubmed/34893694
http://dx.doi.org/10.1038/s42003-021-02914-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664950/
https://www.ncbi.nlm.nih.gov/pubmed/34893694
http://dx.doi.org/10.1038/s42003-021-02914-4

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