A 3D Structural SARS-CoV-2-Human Interactome to Explore Genetic and Drug Perturbations

Emergence of new viral agents is driven by evolution of interactions between viral proteins and host targets. For instance, increased infectivity of SARS-CoV-2 compared to SARS-CoV-1 arose in part through rapid evolution along the interface between the Spike protein and its human receptor ACE2, lead...

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Detalles Bibliográficos
Autores principales: Wierbowski, Shayne D., Liang, Siqi, Liu, Yuan, Chen, You, Gupta, Shagun, Andre, Nicole M., Lipkin, Steven M., Whittaker, Gary R., Yu, Haiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665054/
https://www.ncbi.nlm.nih.gov/pubmed/34845387
http://dx.doi.org/10.1038/s41592-021-01318-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665054/
https://www.ncbi.nlm.nih.gov/pubmed/34845387
http://dx.doi.org/10.1038/s41592-021-01318-w

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