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Aged Nrf2-Null Mice Develop All Major Types of Age-Related Cataracts

PURPOSE: Age-related cataracts affect the majority of older adults and are a leading cause of blindness worldwide. Treatments that delay cataract onset or severity have the potential to delay cataract surgery, but require relevant animal models that recapitulate the major types of cataracts for thei...

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Detalles Bibliográficos
Autores principales: Rowan, Sheldon, Jiang, Shuhong, Francisco, Sarah G., Pomatto, Laura C. D., Ma, Zhiwei, Jiao, Xiaodong, Campos, Maria M., Aryal, Sandeep, Patel, Shaili D., Mahaling, Binapani, Riazuddin, S. Amer, Duh, Elia J., Lachke, Salil A., Hejtmancik, J. Fielding, de Cabo, Rafael, FitzGerald, Paul G., Taylor, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665303/
https://www.ncbi.nlm.nih.gov/pubmed/34882206
http://dx.doi.org/10.1167/iovs.62.15.10