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Bruton’s tyrosine kinase drives neuroinflammation and anxiogenic behavior in mouse models of stress

BACKGROUND: Current therapies targeting several neurotransmitter systems are only able to partially mitigate the symptoms of stress- and trauma-related disorder. Stress and trauma-related disorders lead to a prominent inflammatory response in humans, and in pre-clinical models. However, mechanisms u...

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Detalles Bibliográficos
Autores principales: Ghosh, Simantini, Mohammed, Zaidan, Singh, Itender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665324/
https://www.ncbi.nlm.nih.gov/pubmed/34895246
http://dx.doi.org/10.1186/s12974-021-02322-9