Cargando…

Identification of TRAMs as sphingolipid-binding proteins using a photoactivatable and clickable short-chain ceramide analog

Ceramide is a lipid molecule that regulates diverse physiological and pathological reactions in part through inverting the topology of certain transmembrane proteins. This topological inversion is achieved through regulated alternative translocation (RAT), which reverses the direction by which membr...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Yaqin, You, Lin, Lu, Yong, Han, Sungwon, Wang, Jingcheng, Vicas, Nikitha, Chen, Chuo, Ye, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665359/
https://www.ncbi.nlm.nih.gov/pubmed/34793833
http://dx.doi.org/10.1016/j.jbc.2021.101415