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miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis

ATP-binding cassette, subfamily B member 11 (ABCB11) is an efflux transporter for bile acids on the liver canalicular membrane. The expression of this transporter is reduced in cholestasis; however, the mechanisms contributing to this reduction are unclear. In this study, we sought to determine whet...

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Detalles Bibliográficos
Autores principales: Balasubramaniyan, Natarajan, Devereaux, Michael W., Orlicky, David J., Sokol, Ronald J., Suchy, Frederick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665360/
https://www.ncbi.nlm.nih.gov/pubmed/34774795
http://dx.doi.org/10.1016/j.jbc.2021.101400