Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization

The elongated cilia of the outer segment of rod and cone photoreceptor cells can contain concentrations of visual pigments of up to 5 mM. The rod visual pigments, G protein–coupled receptors called rhodopsins, have a propensity to self-aggregate, a property conserved among many G protein–coupled rec...

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Detalles Bibliográficos
Autores principales: Getter, Tamar, Kemp, Albert, Vinberg, Frans, Palczewski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665362/
https://www.ncbi.nlm.nih.gov/pubmed/34774799
http://dx.doi.org/10.1016/j.jbc.2021.101401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665362/
https://www.ncbi.nlm.nih.gov/pubmed/34774799
http://dx.doi.org/10.1016/j.jbc.2021.101401

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