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Phosphoinositide regulates dynamic movement of the S4 voltage sensor in the second repeat in two-pore channel 3
The two-pore channels (TPCs) are voltage-gated cation channels consisting of single polypeptides with two repeats of a canonical 6-transmembrane unit. TPCs are known to be regulated by various physiological signals such as membrane voltage and phosphoinositide (PI). The fourth helix in the second re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665364/ https://www.ncbi.nlm.nih.gov/pubmed/34800436 http://dx.doi.org/10.1016/j.jbc.2021.101425 |