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Phosphoinositide regulates dynamic movement of the S4 voltage sensor in the second repeat in two-pore channel 3

The two-pore channels (TPCs) are voltage-gated cation channels consisting of single polypeptides with two repeats of a canonical 6-transmembrane unit. TPCs are known to be regulated by various physiological signals such as membrane voltage and phosphoinositide (PI). The fourth helix in the second re...

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Detalles Bibliográficos
Autores principales:	Hirazawa, Kiichi, Tateyama, Michihiro, Kubo, Yoshihiro, Shimomura, Takushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665364/ https://www.ncbi.nlm.nih.gov/pubmed/34800436 http://dx.doi.org/10.1016/j.jbc.2021.101425

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