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Nafamostat mesylate overcomes endocrine resistance of breast cancer through epigenetic regulation of CDK4 and CDK6 expression

Breast cancer is common worldwide, and the estrogen receptor-positive subtype accounts for approximately 70% of breast cancer in women. Tamoxifen and fulvestrant are drugs currently used for endocrinal therapy. Breast cancer exhibiting endocrine resistance can undergo metastasis and lead to the deat...

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Detalles Bibliográficos
Autores principales: Lin, Yueh-Te, Lin, Joseph, Liu, Yi-En, Hsu, Kai-Wen, Hsieh, Chang-Chi, Chen, Dar-Ren, Wu, Han-Tsang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665409/
https://www.ncbi.nlm.nih.gov/pubmed/34890965
http://dx.doi.org/10.1016/j.tranon.2021.101302