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Nafamostat mesylate overcomes endocrine resistance of breast cancer through epigenetic regulation of CDK4 and CDK6 expression
Breast cancer is common worldwide, and the estrogen receptor-positive subtype accounts for approximately 70% of breast cancer in women. Tamoxifen and fulvestrant are drugs currently used for endocrinal therapy. Breast cancer exhibiting endocrine resistance can undergo metastasis and lead to the deat...
Autores principales: | Lin, Yueh-Te, Lin, Joseph, Liu, Yi-En, Hsu, Kai-Wen, Hsieh, Chang-Chi, Chen, Dar-Ren, Wu, Han-Tsang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665409/ https://www.ncbi.nlm.nih.gov/pubmed/34890965 http://dx.doi.org/10.1016/j.tranon.2021.101302 |
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