The antidiabetic drug metformin acts on the bone microenvironment to promote myeloma cell adhesion to preosteoblasts and increase myeloma tumour burden in vivo

Multiple myeloma is a haematological malignancy that is dependent upon interactions within the bone microenvironment to drive tumour growth and osteolytic bone disease. Metformin is an anti-diabetic drug that has attracted attention due to its direct antitumor effects, including anti-myeloma propert...

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Detalles Bibliográficos
Autores principales: Gámez, Beatriz, Morris, Emma V., Olechnowicz, Sam W.Z., Webb, Siobhan, Edwards, James R., Sowman, Aneka, Turner, Christina J., Edwards, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665410/
https://www.ncbi.nlm.nih.gov/pubmed/34890968
http://dx.doi.org/10.1016/j.tranon.2021.101301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665410/
https://www.ncbi.nlm.nih.gov/pubmed/34890968
http://dx.doi.org/10.1016/j.tranon.2021.101301

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