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Involvement of lncRNA IL21-AS1 in interleukin-2 and T follicular regulatory cell activation in systemic lupus erythematosus

BACKGROUND: The single nucleotide polymorphism (SNP) rs62324212, located in IL21 antisense RNA 1 (IL21-AS1), has been identified as a genetic risk variant associated with systemic lupus erythematosus (SLE). We aimed to probe the characteristics of IL21-AS1 and explore its clinical relevance focusing...

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Detalles Bibliográficos
Autores principales: Hao, He, Nakayamada, Shingo, Ohkubo, Naoaki, Yamagata, Kaoru, Zhang, Mingzeng, Shan, Yu, Iwata, Shigeru, Zhang, Tong, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665514/
https://www.ncbi.nlm.nih.gov/pubmed/34895341
http://dx.doi.org/10.1186/s13075-021-02682-w