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Nanoscale characterization of drug-induced microtubule filament dysfunction using super-resolution microscopy

BACKGROUND: The integrity of microtubule filament networks is essential for the roles in diverse cellular functions, and disruption of its structure or dynamics has been explored as a therapeutic approach to tackle diseases such as cancer. Microtubule-interacting drugs, sometimes referred to as anti...

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Detalles Bibliográficos
Autores principales: Rozario, Ashley M., Duwé, Sam, Elliott, Cade, Hargreaves, Riley B., Moseley, Gregory W., Dedecker, Peter, Whelan, Donna R., Bell, Toby D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665533/
https://www.ncbi.nlm.nih.gov/pubmed/34895240
http://dx.doi.org/10.1186/s12915-021-01164-4