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In vivo alterations of mitochondrial activity and amyloidosis in early-stage senescence-accelerated mice: a positron emission tomography study

PURPOSE: While marked reductions in neural activity and mitochondrial function have been reported in Alzheimer’s disease (AD), the degree of mitochondrial activity in mild cognitive impairment (MCI) or early-stage AD remains unexplored. Here, we used positron emission tomography (PET) to examine the...

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Detalles Bibliográficos
Autores principales: Yamagishi, Satoru, Iga, Yurika, Ikegaya, Shunsuke, Kakiuchi, Takeharu, Ohba, Hiroyuki, Nishiyama, Shingo, Fukomoto, Daisuke, Kanazawa, Masakatsu, Harada, Norihiro, Tsukada, Hideo, Sato, Kohji, Ouchi, Yasuomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665644/
https://www.ncbi.nlm.nih.gov/pubmed/34893067
http://dx.doi.org/10.1186/s12974-021-02343-4