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In vivo alterations of mitochondrial activity and amyloidosis in early-stage senescence-accelerated mice: a positron emission tomography study
PURPOSE: While marked reductions in neural activity and mitochondrial function have been reported in Alzheimer’s disease (AD), the degree of mitochondrial activity in mild cognitive impairment (MCI) or early-stage AD remains unexplored. Here, we used positron emission tomography (PET) to examine the...
Autores principales: | Yamagishi, Satoru, Iga, Yurika, Ikegaya, Shunsuke, Kakiuchi, Takeharu, Ohba, Hiroyuki, Nishiyama, Shingo, Fukomoto, Daisuke, Kanazawa, Masakatsu, Harada, Norihiro, Tsukada, Hideo, Sato, Kohji, Ouchi, Yasuomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665644/ https://www.ncbi.nlm.nih.gov/pubmed/34893067 http://dx.doi.org/10.1186/s12974-021-02343-4 |
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