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Founder reconstruction enables scalable and seamless pangenomic analysis
MOTIVATION: Variant calling workflows that utilize a single reference sequence are the de facto standard elementary genomic analysis routine for resequencing projects. Various ways to enhance the reference with pangenomic information have been proposed, but scalability combined with seamless integra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665761/ https://www.ncbi.nlm.nih.gov/pubmed/34260702 http://dx.doi.org/10.1093/bioinformatics/btab516 |