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Founder reconstruction enables scalable and seamless pangenomic analysis

MOTIVATION: Variant calling workflows that utilize a single reference sequence are the de facto standard elementary genomic analysis routine for resequencing projects. Various ways to enhance the reference with pangenomic information have been proposed, but scalability combined with seamless integra...

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Detalles Bibliográficos
Autores principales: Norri, Tuukka, Cazaux, Bastien, Dönges, Saska, Valenzuela, Daniel, Mäkinen, Veli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665761/
https://www.ncbi.nlm.nih.gov/pubmed/34260702
http://dx.doi.org/10.1093/bioinformatics/btab516