Deconvolution of expression for nascent RNA-sequencing data (DENR) highlights pre-RNA isoform diversity in human cells

MOTIVATION: Quantification of isoform abundance has been extensively studied at the mature RNA level using RNA-seq but not at the level of precursor RNAs using nascent RNA sequencing. RESULTS: We address this problem with a new computational method called Deconvolution of Expression for Nascent RNA-...

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Detalles Bibliográficos
Autores principales: Zhao, Yixin, Dukler, Noah, Barshad, Gilad, Toneyan, Shushan, Danko, Charles G, Siepel, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665767/
https://www.ncbi.nlm.nih.gov/pubmed/34382072
http://dx.doi.org/10.1093/bioinformatics/btab582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665767/
https://www.ncbi.nlm.nih.gov/pubmed/34382072
http://dx.doi.org/10.1093/bioinformatics/btab582

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