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Chinese Herbal Medicine Suyin Detoxification Granule Inhibits Pyroptosis and Epithelial-Mesenchymal Transition by Downregulating MAVS/NLRP3 to Alleviate Renal Injury

PURPOSE: Proteinuria is an independent risk factor of chronic kidney disease (CKD). Albumin-induced tubulointerstitial inflammation and epithelial-mesenchymal transition (EMT) via the activation of NLRP3 inflammasome is a potential therapeutic target for CKD. Suyin Detoxification Granule (SDG) impro...

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Detalles Bibliográficos
Autores principales: Zhu, Yiye, Huang, Guoshun, Yang, Yang, Yong, Chen, Yu, Xiang, Wang, Gang, Yi, Lan, Gao, Kun, Tian, Fang, Qian, Shushu, Zhou, Enchao, Zou, Yanqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665879/
https://www.ncbi.nlm.nih.gov/pubmed/34908861
http://dx.doi.org/10.2147/JIR.S341598