Blunted sFasL signalling exacerbates TNF‐driven neutrophil necroptosis in critically ill COVID‐19 patients

OBJECTIVES: Critically ill coronavirus disease 2019 (COVID‐19) patients are characterised by a severely dysregulated cytokine profile and elevated neutrophil counts, impacting disease severity. However, it remains unclear how neutrophils contribute to pathophysiology during COVID‐19. Here, we assess...

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Detalles Bibliográficos
Autores principales: Schweizer, Tiziano A, Mairpady Shambat, Srikanth, Vulin, Clement, Hoeller, Sylvia, Acevedo, Claudio, Huemer, Markus, Gomez‐Mejia, Alejandro, Chang, Chun‐Chi, Baum, Jeruscha, Hertegonne, Sanne, Hitz, Eva, Scheier, Thomas C, Hofmaenner, Daniel A, Buehler, Philipp K, Moch, Holger, Schuepbach, Reto A, Brugger, Silvio D, Zinkernagel, Annelies S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665925/
https://www.ncbi.nlm.nih.gov/pubmed/34938538
http://dx.doi.org/10.1002/cti2.1357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665925/
https://www.ncbi.nlm.nih.gov/pubmed/34938538
http://dx.doi.org/10.1002/cti2.1357

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