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Blunted sFasL signalling exacerbates TNF‐driven neutrophil necroptosis in critically ill COVID‐19 patients
OBJECTIVES: Critically ill coronavirus disease 2019 (COVID‐19) patients are characterised by a severely dysregulated cytokine profile and elevated neutrophil counts, impacting disease severity. However, it remains unclear how neutrophils contribute to pathophysiology during COVID‐19. Here, we assess...
Autores principales: | Schweizer, Tiziano A, Mairpady Shambat, Srikanth, Vulin, Clement, Hoeller, Sylvia, Acevedo, Claudio, Huemer, Markus, Gomez‐Mejia, Alejandro, Chang, Chun‐Chi, Baum, Jeruscha, Hertegonne, Sanne, Hitz, Eva, Scheier, Thomas C, Hofmaenner, Daniel A, Buehler, Philipp K, Moch, Holger, Schuepbach, Reto A, Brugger, Silvio D, Zinkernagel, Annelies S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665925/ https://www.ncbi.nlm.nih.gov/pubmed/34938538 http://dx.doi.org/10.1002/cti2.1357 |
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