Induction of ß Cell Replication by Small Molecule-Mediated Menin Inhibition and Combined PKC Activation and TGF-ß Inhibition as Revealed by A Refined Primary Culture Screening

OBJECTIVE: Pancreatic β cells are recognized as central players in the pathogenesis of types 1 and 2 diabetes. Efficient and robust primary culture methods are required to interrogate β cell biology and screen potential anti-diabetic therapeutics. The aim of this study was to refine monolayer cultur...

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Detalles Bibliográficos
Autores principales: Pahlavanneshan, Saghar, Behmanesh, Mehrdad, Tahamtani, Yaser, Hajizadeh-Saffar, Ensiyeh, Basiri, Mohsen, Baharvand, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665985/
https://www.ncbi.nlm.nih.gov/pubmed/34939756
http://dx.doi.org/10.22074/cellj.2021.7437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665985/
https://www.ncbi.nlm.nih.gov/pubmed/34939756
http://dx.doi.org/10.22074/cellj.2021.7437

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