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Processing binding data using an open-source workflow
The thermal shift assay (TSA)—also known as differential scanning fluorimetry (DSF), thermofluor, and T(m) shift—is one of the most popular biophysical screening techniques used in fragment-based ligand discovery (FBLD) to detect protein–ligand interactions. By comparing the thermal stability of a t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666039/ https://www.ncbi.nlm.nih.gov/pubmed/34895330 http://dx.doi.org/10.1186/s13321-021-00577-1 |