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Processing binding data using an open-source workflow

The thermal shift assay (TSA)—also known as differential scanning fluorimetry (DSF), thermofluor, and T(m) shift—is one of the most popular biophysical screening techniques used in fragment-based ligand discovery (FBLD) to detect protein–ligand interactions. By comparing the thermal stability of a t...

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Detalles Bibliográficos
Autores principales: Samuel, Errol L. G., Holmes, Secondra L., Young, Damian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666039/
https://www.ncbi.nlm.nih.gov/pubmed/34895330
http://dx.doi.org/10.1186/s13321-021-00577-1