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Proteomic discovery in sickle cell disease: Elevated neurogranin levels in children with sickle cell disease

PURPOSE: Sickle cell disease (SCD) is an inherited hemoglobinopathy that causes stroke and silent cerebral infarct (SCI). Our aim was to identify markers of brain injury in SCD. EXPERIMENTAL DESIGN: Plasma proteomes were analyzed using a sequential separation approach of hemoglobin (Hb) and top abun...

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Detalles Bibliográficos
Autores principales: Lance, Eboni I., Faulcon, Lisa M., Fu, Zongming, Yang, Jun, Whyte-Stewart, Donna, Strouse, John J., Barron-Casella, Emily, Jones, Kimberly, Van Eyk, Jennifer E., Casella, James F., Everett, Allen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666096/
https://www.ncbi.nlm.nih.gov/pubmed/33915030
http://dx.doi.org/10.1002/prca.202100003