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LRRC8A is essential for volume‐regulated anion channel in smooth muscle cells contributing to cerebrovascular remodeling during hypertension

OBJECTIVES: Recent studies revealed LRRC8A to be an essential component of volume‐regulated anion channel (VRAC), which regulates cellular volume homeostasis. However, evidence for the contribution of LRRC8A‐dependent VRAC activity in vascular smooth muscle cells (VSMCs) is still lacking, and the re...

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Detalles Bibliográficos
Autores principales: Li, Xiang‐Yu, Lv, Xiao‐Fei, Huang, Cheng‐Cui, Sun, Lu, Ma, Ming‐Ming, Liu, Canzhao, Guan, Yong‐Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666279/
https://www.ncbi.nlm.nih.gov/pubmed/34725866
http://dx.doi.org/10.1111/cpr.13146