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Adenoviral VEGF-B186R127S gene transfer induces angiogenesis and improves perfusion in ischemic heart

Vascular endothelial growth factor B (VEGF-B) is an interesting therapeutic candidate for coronary artery disease. However, it can also cause ventricular arrhythmias, potentially preventing its use in clinics. We cloned VEGF-B isoforms with different receptor binding profiles to clarify the roles of...

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Detalles Bibliográficos
Autores principales: Korpela, Henna, Hätinen, Olli-Pekka, Nieminen, Tiina, Mallick, Rahul, Toivanen, Pyry, Airaksinen, Jonna, Valli, Kaisa, Hakulinen, Mikko, Poutiainen, Pekka, Nurro, Jussi, Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666349/
https://www.ncbi.nlm.nih.gov/pubmed/34917905
http://dx.doi.org/10.1016/j.isci.2021.103533