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Adenoviral VEGF-B186R127S gene transfer induces angiogenesis and improves perfusion in ischemic heart
Vascular endothelial growth factor B (VEGF-B) is an interesting therapeutic candidate for coronary artery disease. However, it can also cause ventricular arrhythmias, potentially preventing its use in clinics. We cloned VEGF-B isoforms with different receptor binding profiles to clarify the roles of...
Autores principales: | Korpela, Henna, Hätinen, Olli-Pekka, Nieminen, Tiina, Mallick, Rahul, Toivanen, Pyry, Airaksinen, Jonna, Valli, Kaisa, Hakulinen, Mikko, Poutiainen, Pekka, Nurro, Jussi, Ylä-Herttuala, Seppo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666349/ https://www.ncbi.nlm.nih.gov/pubmed/34917905 http://dx.doi.org/10.1016/j.isci.2021.103533 |
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