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Plasminogen Activating Inhibitor-1 Might Predict the Efficacy of Anti-PD1 Antibody in Advanced Melanoma Patients

Plasminogen activating inhibitor-1 (PAI-1) plays crucial roles in the development of various cancers, including melanomas. Indeed, various pro-tumorigenic functions of PAI-1 in cancer progression and metastasis have been widely reported. Among them, PAI-1 is also reported as a key regulator of PD-L1...

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Detalles Bibliográficos
Autores principales: Ohuchi, Kentaro, Kambayashi, Yumi, Hidaka, Takanori, Fujimura, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666429/
https://www.ncbi.nlm.nih.gov/pubmed/34912726
http://dx.doi.org/10.3389/fonc.2021.798385