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Precise Identification of Recurrent Somatic Mutations in Oral Cancer Through Whole-Exome Sequencing Using Multiple Mutation Calling Pipelines

Understanding the genomic alterations in oral carcinogenesis remains crucial for the appropriate diagnosis and treatment of oral squamous cell carcinoma (OSCC). To unveil the mutational spectrum, in this study, we conducted whole-exome sequencing (WES), using six mutation calling pipelines and multi...

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Detalles Bibliográficos
Autores principales: Lin, Li-Han, Chou, Chung-Hsien, Cheng, Hui-Wen, Chang, Kuo-Wei, Liu, Chung-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666431/
https://www.ncbi.nlm.nih.gov/pubmed/34912705
http://dx.doi.org/10.3389/fonc.2021.741626