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Cross-talk of inflammatory mediators and airway epithelium reveals the cystic fibrosis transmembrane conductance regulator as a major target

Airway inflammation, mucus hyperproduction and epithelial remodelling are hallmarks of many chronic airway diseases, including asthma, COPD and cystic fibrosis. While several cytokines are dysregulated in these diseases, most studies focus on the response of airways to interleukin (IL)-4 and IL-13,...

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Detalles Bibliográficos
Autores principales: Simões, Filipa B., Kmit, Arthur, Amaral, Margarida D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666577/
https://www.ncbi.nlm.nih.gov/pubmed/34912883
http://dx.doi.org/10.1183/23120541.00247-2021