Discovery of a Novel MyD88 Inhibitor M20 and Its Protection Against Sepsis-Mediated Acute Lung Injury

Myeloid differentiation factor 88 (MyD88) is a hub protein in the Toll-like receptor signaling pathway, which acts as a master switch for numerous inflammatory diseases, including acute lung injury (ALI). Although this protein is considered as a crucial therapeutic target, there are currently no cli...

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Detalles Bibliográficos
Autores principales: Song, Jiali, Chen, Daoxing, Pan, Yingqiao, Shi, Xueqin, Liu, Qian, Lu, Xiaoyao, Xu, Ximing, Chen, Gaozhi, Cai, Yuepiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666603/
https://www.ncbi.nlm.nih.gov/pubmed/34912226
http://dx.doi.org/10.3389/fphar.2021.775117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666603/
https://www.ncbi.nlm.nih.gov/pubmed/34912226
http://dx.doi.org/10.3389/fphar.2021.775117

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