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Endothelial dysfunction and hypercoagulability in severe sickle-cell acute chest syndrome

RATIONALE: Acute pulmonary hypertension (PH) may develop during sickle-cell acute chest syndrome (ACS), and is associated with an increased mortality. Its mechanisms remain poorly known. We questioned whether there is endothelial dysfunction and hypercoagulability in severe ACS, with and without acu...

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Detalles Bibliográficos
Autores principales: Jutant, Etienne-Marie, Voiriot, Guillaume, Labbé, Vincent, Savale, Laurent, Mokrani, Hayat, Van Dreden, Patrick, Gerotziafas, Grigorios, Fartoukh, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666627/
https://www.ncbi.nlm.nih.gov/pubmed/34912886
http://dx.doi.org/10.1183/23120541.00496-2021