Allosteric regulation of binding specificity of HVEM for CD160 and BTLA ligands upon G89F mutation

Molecular interactions mediated by engagement of the Herpes virus entry mediator (HVEM) with members of TNF and Ig superfamily generate distinct signals in T cell activation pathways that modulate inflammatory and inhibitory responses. HVEM interacts with CD160 and B and T lymphocyte attenuator (BTL...

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Detalles Bibliográficos
Autores principales: Shrestha, Rojan, Garrett-Thomson, Sarah, Liu, Weifeng, Almo, Steven C., Fiser, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666650/
https://www.ncbi.nlm.nih.gov/pubmed/34917954
http://dx.doi.org/10.1016/j.crstbi.2021.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666650/
https://www.ncbi.nlm.nih.gov/pubmed/34917954
http://dx.doi.org/10.1016/j.crstbi.2021.11.001

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